In the dramatically changing world where the rates of change follow Moore's Law, determining that the number of transistors on a chip, managing data, doubles every two years, the digital revolution will be a key factor in the redesigning of our cities. With life-styles and patterns of living responding to the new models of urbanization, the need to consider geo-cultural values and attitudes is essential. The current texts for managing human settlement now include, inter alia, the Sustainable Development Goals, the New Urban Agenda and the Recommendation on the Historic Urban Landscape. Applying these concepts to address the challenges of mobility, inclusiveness, resilience and safety is critical in Macao being inscribed on the World Heritage List and in managing the development pressures of global tourism and an extended metropolis of the Pearl River. New technologies, virtual realities, artificial intelligence will change our cities, for better and worse.